Type 1 peritoneal membrane failure in a paediatric patient, successfully treated with icodextrin

Introduction: Studies in adults demonstrate type I ultrafiltration failure (UFF) more common type rather than type 2, 3 and type 4 UFF. But in contrast, the incidence of type 1 UFF in children and its management with icodextrin are rarely described. Case presentation: We describe the type 1 UFF in a case of a 10-year-old boy who was diagnosed with end stage renal failure on Nocturnal intermittent peritoneal dialysis (NIPD) secondary to genetic proved (NPHS1) congenital nephrotic syndrome. His peritoneal equilibrium test (PET) revealed type 1 UFF. Subsequently, he was managed with icodextrin and responded dramatically to our therapy. Although type I membrane failure is well evident in adult populations, acquiring the same in a paediatric child is very limited. Moreover, icodextrin is one of the choices in managing type 1 UFF in adults. But, there have been no case reports in paediatric patients. Conclusions: Type 1 UFF can occur in a paediatric child, as its cause remains unknown. Early diagnosis and prompt management can be essential to improving the quality of patient care in peritoneal dialysis. Icodextrin may provide an effective modality of treatment. Correspondence to: Mohammed Azar, Department of Pediatrics, Division of Nephrology, King Abdulaziz Medical City, King Abdullah Specialized Children Hospital, Mail Code 1940, Riyadh, P. O. Box 22490, Riyadh 11426, Kingdome of Saudi Arabia, Tel: +966-118011111Ext53524, E-mail: shameemazar@gmail. com